Cefprozil Oral Suspension Dispenser

Pediatric Dosing Information

The current Prescribing Information (PI), for the dosing administration of Cefprozil oral suspension for pediatric patients 12 years or younger recite; a recommended dose of 7.5 mg/kg or 15.0 mg/kg. The PI furthers describes that each teaspoon (5 mL) contains 125 mg of anhydrous Cefprozil.1

The PI does not describe the extrapolation of 7.5 mg/kg or 15.0 mg/kg from the 5 mL – 125 mg suspension and/or teaspoon (6% – 12%), nor for the subsequent conversion of the milligrams of suspension to an individual kilogram patient dose as prescribed.  Moreover, dozens of studies conclude that a household teaspoon is not an adequate measuring device.2 According to the American Academy of Pediatrics (AAP) and the US Food and Drug Administration (FDA), among other health agencies, non-standard kitchen spoons are not recommended as a dosing apparatus for medicinal solutions. 2,3,4,5

The Dose-Weight Syringe® is specifically calibrated to administer a patient specific dose of Cefprozil oral suspension to the optimal dose of 7.5 mg/kg or 15.0 mg/kg to an individualized pediatric patient weight as clinically recommended.

1 https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=3ec55c0a-1456-412e-972f-352b3135c8f2&type=display#ID92
2 Yin HS, Parker RM, Sanders LM, et al. Liquid Medication Errors and Dosing Tools: A Randomized Controlled Experiment. Pediatrics. 2016;138(4):e20160357. doi:10.1542/peds.2016-0357
Shah R, Blustein L, Kuffner E, Davis L. Communicating doses of pediatric liquid medicines to parents/caregivers: a comparison of written dosing directions on prescriptions with labels applied by dispensed pharmacy. J Pediatr. 2014;164(3):596–601, e591 [PubMed] [Google Scholar]
McMahon SR, Rimsza ME, Bay RC. Parents can dose liquid medication accurately. Pediatrics. 1997;100(3 pt 1):330–333 [PubMed] [Google Scholar]
5 Yaffe SJ, Bierman CW, Cann HM, et al. . Inaccuracies in administering liquid medication. Pediatrics. 1975;56(2):327–328 [PubMed] [Google Scholar]
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All labeling and dosing representation on this website is for informational and promotional purposes only.  It should not be used for prescribing or administering these products. Please contact your physician or a health care professional for all preparation and administration directions.