At Asepsis, we understand the intricacies involved with drug discovery and the criticality of optimal dosing.  We also understand that despite sophisticated pharmacokinetic and pharmacodynamic modeling to develop these dosing regimens, medications are far too often inaccurately administered. Statistically, the leading factors of these inaccuracies are sequence and procedural error, thus resulting in the deviation of a manufacturer’s preparation and administration instructions.  As such, despite best efforts, human factors often dictate the standard of patient care.

It is at this juncture where Asepsis’ drug delivery systems provide for proprietary solutions to enable health care providers the tools to rapidly and intuitively prepare and administer a medication – at the correct concentration to an individualized optimal dose. This consistent precision adherence to a manufacturer’s preparation and administration instructions, provides for the highest standard of patient care during treatment with the specific medication.

Statistics portray that over 1,000 people die per day as a result of preventable medical errors, making it the third leading cause of death in America1; and that on average, a hospital patient is subject to at least one medication error per day2; and that the United States Food and Drug Administration (FDA) evaluated reports received of fatal medication errors and found that the most common types of errors involved the administration of an improper dose (41%), administering the wrong drug (16%), and using the wrong route of administration (16%), with injectable drugs raising the most problems3.

mike-and-liv-1024x790 CEO

The statistics identify that multiple hands-on procedures for the consolidation and correlation of the required components, reconstitution procedures, and the calculation and preparation of the correct dose according to a specific patient characteristic (within an already complex environment), exponentially increases the potential for a medical error. In fact, according to a Medical Error Program operated by the U.S. Pharmacopeia and the Institute for Safe Medication Practices, confusion caused by similar drug names accounts for up to 25% of all errors reported. In addition, labeling and packaging issues were cited as the leading cause of 33% of all errors, including 30% of all fatalities.4

The severity of these statistics can only be exacerbated by the fact the studies also indicate pediatric patients are up to three times more likely to have an adverse drug event than adults from these errors5.  These statistics should provide for an industry catalyst to  enhance and provide safer, more precise, intuitive packaging and delivery apparatus to health care providers. Reducing preventable medication error should start before the medication reaches any health-care provider and certainly well before the patient.

Whether dosing according to patient characteristics (e.g., BSA or weight), and/or small volume dose in (e.g., mcg, mg, IU, mL), our proprietary technology provides over-the-counter oral solutions with the same platform used for highly potent injectable medications for small mass neonates. There are no, “just abouts”, “patient ranges” or “adjustments for dosing convenience” – solely, precisely as prescribed.

I wish to personally thank you for your interest in our company and our mission to enhance patient safety and outcome through higher precision medication delivery.


Michael Creaturo
CEO and Managing Partner

1 McCann, Erin, “Deaths by Medical Mistakes Hit Records”,,
2 “Summary”. Preventing Medication Errors: Quality Chasm Series. Washington, DC: The National Academies Press, 2007.
3 “Strategies to Reduce Medication Errors: Working to Improve Medication Safety”.
4 Pham, J. C., Story, J. L., Hicks, R. W., et al. (2011). National study on the frequency, types, causes, and consequences of voluntarily reported emergency department medication errors.
5 Mendelsohn, A. B., Schroeder, T. J., Annest, J. L. (2006). National surveillance of emergency department visits for outpatient adverse drug events. Journal of the American Medical.

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